The progress of mankind has been punctuated with some deadliest pandemics. Several ominous diseases have decimated a large chunk of the population of earth. These diseases – termed as a Pandemics – are infectious spreading through large regions, for instance, multiple continents or even worldwide. In most cases the breakout is severe and rapid bringing humanity to its knees, gasping for survival. Here is a compilation of some of the most harrowing pandemics which are known to have had a devastating impact on humanity.